Archive for the ‘Cancer’ Category
Generally, moles, which are often attractive and sometimes unpleasant, are not usually dangerous. But in exceptional cases, one of the innocent little dots moving towards a form of skin cancer very serious melanoma. Although melanotic tumors are benign neoplasms are frequent clinical malignant pigment like Melanosarcoma. But how can we know when a mole is dangerous?
The American Academy of Dermatology advises that you visit your doctor if you have moles with the following characteristics:
a. Any mole that has not been present since birth and is palpable.
b. Any mole that suddenly this rapid growth.
c. Those who change their shape.
d. Those whose position is easily irritated.
e. All lunar blood.
f. Those who by their location can not be easily observed, as would those in the scalp, anogenital region or mucous membranes.
g. Any mole that appears after age 30.
h. Those that produce itching or pain.
A publication in Madrid, Europa Press reveals that the pancreatic ductal adenocarcinoma, or ADP, is a very deadly form of cancer, but researchers at the School of Medicine, University of Pennsylvania in Philadelphia (USA) show that a combination of chemotherapy and a drug that activates the CD40 protein can shrink tumors effectively in a subset of human patients and mice. Their work is published in the journal Science.
The scientists, led by Gregory Beatty, report the results of a clinical trial in which a small number of patients with incurable ADP surgical inland benefited from immunotherapy with CD40. The treatment appeared to slow the progression of cancer in patients for a median of 5.6 months.
The researchers then analyzed this treatment in mice that were genetically engineered to have ADP and found that a subgroup of mice also responded well.
Since it is known that CD40 promotes T cells deletion eliminating the cancer of immune system function, researchers was surprised to discover that the antitumor effects providing this immunotherapy with macrophages involving CD40. Macrophages were activated by CD40 is rapidly infiltrating the tumors and facilitated the removal of the tumor tissue.
These findings suggest that T cells induced by therapy were not necessary to activate the immune system against cancer cells. Conclude that activation of macrophages with CD40 may provide a means of launching anti-tumor immunity in the ADP.
The pituitary gland is a small gland about the size and shape of a pea. It is located between the eyes, behind the bridge of the nose, just below the brain. The pituitary lies within a bony depression in the skull called the sella, which sits below the optic chiasm, the area where the nerves of the eyes (optic nerves) cross and enter the brain. It is often referred to as the “master” gland of the body, because it produces hormones that control many other glands throughout the body, including the thyroid gland, adrenal glands and sex organs (ovaries and testes).
Hormones produced by the pituitary gland
in the posterior lobe, there are two different hormones:
1. ADH acts on the kidneys to release water through the urine.
2. Oxytocin acts primarily in the uterus to stimulate contractions. It may also act on the breasts to stimulate milk secretion.
In the anterior lobe, several different types of hormones are produced:
* Growth hormones stimulate growth in children and play an important role in regulating metabolism and processing of proteins, fats, and carbohydrates in the body.
* Prolactin acts primarily in the breast to stimulate milk production. It also plays a role in the development of eggs in the ovaries of a woman and can help regulate the immune system.
* Adrenocorticotropic hormone stimulates the growth of the adrenal glands, which are located just above the kidneys.
* Stimulating hormone thyroid secretion acts on the thyroid gland to stimulate the production of thyroid hormone. Thyroid hormone is the main regulator of overall metabolism in the body.
* Luteinizing hormone acting on the gonads (testes in men and ovaries in women). In men, LH causes the testicles to produce testosterone, the primary male hormone, while FSH regulates the production of sperm. In women, LH causes the ovaries to produce estrogen, the primary female hormone, and also plays an important role in stimulating the release of eggs from the ovary.
British scientists say they have found a gene that promotes the spread of most cancers, which WWP2 pharmacological blockade could represent a breakthrough in the fight against the disease.
The finding is the work of a team from the University of East Anglia led by Dr Andrew Chantry, who says that the identification of this gene may give way to medical solutions within a decade to stop the most aggressive cancers.
These cancers include breast, brain, colon and skin, spread especially fast.
“The challenge now is to identify a potent drug invasive cancer cells, destroying the activity of the defective gene,” says Chantry, whose work is published in the latest edition of the medical journal Oncogene.
“We have begun to experiment with a molecule that we think can do the job. If that’s the case, we will lay the foundations for a new generation of a single drug for various cancers,” said the expert.
The WWP2 is the product of an enzyme that binds the chemical elements within the cells and is present in all human bodies. “We all have the gene, but when defective hijacks this process and helps the cancer grow and spread to other parts of the body. This is what eventually kills,” said Dr. Chantry.
In case you develop a drug that deactivates the WWP2, conventional therapies and surgery may limit the primary cancerous tumors without the risk of being installed in other parts of the body.
Dr. Chantry forecast that this treatment is less invasive and has fewer side effects can be applied within five to ten years. Cancer Resarch Group (Cancer Research) in the United Kingdom welcomed the finding, but with some caution.
“In recent decades, researchers around the world have discovered genes that drive the growth and spread of cancer and this research is one in a list that keeps growing,” said Kat Arney, a spokesman for the organization.
Cancer can occur anywhere in the brain or spinal cord. Cancer cells are abnormal cells that divide too often and without any order.
Workers in oil refining, rubber manufacturing, and drug manufacturing industries have higher rates of certain types of brain tumors.
Symptoms cerebroLos tumors symptoms of primary brain tumors and metastatic depend mainly on location in the brain and tumor size. Since each brain area is responsible for specific functions, symptoms vary greatly. Tumors in the frontal lobe of the brain can cause weakness and inability to move on one side of the body, known as paralysis, mood disturbances, difficulty thinking, confusion and disorientation, and wide emotional mood swings. Parietal lobe tumors can cause seizures, numbness or paralysis, difficulty with handwriting, inability to perform simple mathematical problems, difficulty with certain movements, and loss of sense of touch. Tumors in the occipital lobe can cause vision loss in half of each field of vision, visual hallucinations, and seizures.
Is the growth of cancer cells in the tissues of the brain can destroy brain cells and also cause damage to cells by inflammation and compression to the tumor growth and can cause cerebral edema.
TYPES OF TUMORS
* Astrocytoma: originate in cells called astrocytes that vary in degree of malignancy.
* Oligodendroglial tumors arise from brain cells oligodendrocytes.
* Glioblastoma Multiforme: also known as grade IV astrocytoma, has developed rapidly.
* Ependymomas: it originates in the ependyma, an area that produces and stores the cerebrospinal fluid.
* Mixed Gliomas they evolve in more than one type of cell, such as cells of astrocytes, oligodendrocytes and cells or ependymal cells.
SYMPTOMS
Headache.
* Vomiting.
* Difficulty walking.
* Difficulty speaking.
* Changes in vision, double vision.
* Weight gain.
* Seizures.
* Hearing problems
* Trouble concentrating.
Fever.
* Difficulty coordinating movements.
* Lack of reflections.
* Facial paralysis
Difficulty swallowing
* Earthquakes.
* Facial paralysis.
Cancer Institute Dana-Farber in the U.S. and a team of researchers has been able to find a new chromosomal mechanism may be involved in cancer development.
The investigation and its findings are published in the online edition of the journal Nature, which also explains how the new molecular mechanism could weave chromosomal instabilities are usually observed in cancer cells.
Importantly, cancer cells have an abnormal set of chromosomes made up of extra centrosomes, which according to scientific research developers could promote abnormal separation of chromosomes, chromosome instability and proliferation of malignant cells.
David Pellman, who led the research, said that the abnormal segregation arises because the chromosomes cannot properly join with the axis of division, a process name merotely, which has also been linked to chromosomal instability.
The increase in cases of kidney cancer has doubled the rate of 7 per 100,000 populations in 1975 to 12/100.000 today.
This has given rise especially among women who smoke risk increasing the chances of tumor by 35 percent.
The information has been provided in the 34 th National Congress of the Spanish Association of Urology (EAU) in Feria Valencia, adding further data related to the increase in victims of cancer as a result of changing lifestyles, poor diet and inactivity.
The determinants of tumors respond to a hereditary component, so that affects men and women have double the incidence in males. But women have increased in number as a result of smoking.
The detection of these tumors but today it is more accurate with new imaging techniques.
The annual increase is caused in turn by the currently offered better diagnosis of tumors and increased in younger people as a result of smoking, for example.
Yet it is undeniable that the removal of tumors in time can turn into a better appreciation of life.
one question that often stand in the forefront of most people at some time since some time is whether mobile phones cause cancer. It is often said that the antennas of mobile telephony radiation generated by producing certain diseases, especially cancer.
The reality is that no one could determine with certainty whether it was true that premise, so the World Health Organization got down to work to clarify the uncertainties regarding the issue.
In 10 years, the World Health Organization conducted a study that found that cancer development is closely related to the use and frequent exposure to mobile phones. The reality is that a person who spends half an hour in contact with a cell phone increases your chances of developing a type of brain tumor called glioma.
On the other hand, the director of the International Agency for Research on Cancer (IARC), Christopher Wild, said the study conducted by the World Health Organization was not quite feasible for two important reasons. First, 10 years ago mobile phones did not have the sophistication to have the equipment now, not to mention that at present this service is spread widely.
On the other hand, Wild said that there was no device to measure the time people were in contact with their mobile phones, but the results were based simply on what each individual could remember and tell.
It is also important to note that in recent days conducted a study where pregnant women were analyzed that was exposed to antennas and wireless receiving stations frequently. They concluded that there was no connection between the mobile contact and the appearance of tumors.
In Argentina, a group of scientists developed a milk that is not a medicine, but say it is effective in preventing heart disease, diabetes and malignant tumors, mainly in the breast and ovaries.
The ‘super milk’ is a mixture of cow’s milk with goat milk, which is the product of the efforts of researchers Argentine National Institute of Agricultural Technology.
The origin of milk
The method followed by the developers was mainly based on strict control of feeding cows and goats that produce milk, whose diet was based on fish oil, soy milk and soy.
The result is a milk high in conjugated linoleic acid (CLA) and fatty vacénico (AV), which decreases the chance of developing tumors and diabetes and prevent the formation of blockages in the arteries.