Cancer Institute Dana-Farber in the U.S. and a team of researchers has been able to find a new chromosomal mechanism may be involved in cancer development.
The investigation and its findings are published in the online edition of the journal Nature, which also explains how the new molecular mechanism could weave chromosomal instabilities are usually observed in cancer cells.
Importantly, cancer cells have an abnormal set of chromosomes made up of extra centrosomes, which according to scientific research developers could promote abnormal separation of chromosomes, chromosome instability and proliferation of malignant cells.
David Pellman, who led the research, said that the abnormal segregation arises because the chromosomes cannot properly join with the axis of division, a process name merotely, which has also been linked to chromosomal instability.
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Cancer Institute Dana-Farber in the U.S. and a team of researchers has been able to find a new chromosomal mechanism may be involved in cancer development.